NITABOH: Tsugaru Shamisen Shiso Gaibun

At a young age, Nitaroh is stricken with an illness that leaves him blind. He inherits the shamisen guitar once used by his mother and is taught its basics by a blind travelling shamisen player. In time with the help of friends old and new, he walks the paths that leads to his ultimate fate - that of founder of the Tsugaru style of shamisen play.
(Source: Anime News Network)