Baka to Alpha no Kenkyuushitsu

The population of Alphas and Omegas were on the decline and research about the second sex was stagnant. Yohta, an Omega, was conducting various experiments using himself as a specimen, hoping to become an Alpha. His goal was to remain best friends with his childhood friend and Alpha, Shigeyuki! For the sake of his friend's wish, Shigeyuki goes along with Yohta's crazy experiments, But Shigeyuki secretly has special feelings for Yohta...
(Source: Marble Comics, translated)