Ginga: Nagareboshi Gin

A giant demon bear named Akakabuto has taken over Futago pass. Shortly after, a silver, tiger-striped Akita pup named Gin is born and is trained as a bear-dog. Gin is brought to Riki (the leader of a large pack of dogs and Gin's father) to join the pack. Riki let's him join after proving his strenght and sends his platoons to all parts of Japan to recruit strong males to fight Akakabuto.
Gin, the third generation of bear-dogs goes through many hardships for the purpose of stopping the terrifying bear, Akakabuto.
(Source: AnimeNewsNetwork)